Anti-Itch patch includes a flexible backing have a front and back side. A therapeutic formulation is positioned on at least a portion of the front side of the backing. The therapeutic formulation includes a medicament, useful for treating a condition associated with an insect bite, a rash, a skin irritation, poison ivy, poison oak, an inflammatory skin condition, or poison sumac and a pressure sensitive adhesive. The method includes applying to the skin surface of the patient in need of such treatment an adhesive patch of the present invention. The adhesive patch effectively treats a condition associated with the insect bite, the rash, the skin irritation, the poison ivy, the poison oak or the inflammatory skin condition.