Profile: Berna Products Corp supplies oral vaccines. We offer oral typhoid fever vaccine vivotif berna, which is a live oral ty21a typhoid vaccine & tetanus toxoid adsorbed vaccines, which give pain free protection for international travelers. Our Vivotif is a live attenuated vaccine for oral administration only. The vaccine contains the attenuated strain Salmonella typhi Ty21a. The vaccine strain is grown in fermentors under controlled conditions in medium containing a digest of yeast extract, an acid digest of casein, dextrose and galactose. The bacteria are collected by centrifugation, mixed with a stabilizer containing sucrose, ascorbic acid and amino acids, and lyophilized. The lyophilized bacteria are mixed with lactose and magnesium stearate & filled into gelatin capsules which are coated with an organic solution to render them resistance to dissolution in stomach acid. The enteric-coated, salmon/white capsules are then packaged in 4-capsule blisters for distribution.
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