Profile: Entrogen is a bio-technology company that deals with genotyping assays in the areas of pharmacogenomics and oncology. We offer Kras mutation test kit, Warfarin sensitivity test, irinotecan toxicity test and 5-FU toxicity test. Our Kras gene encodes a small GTPase that enables transducing signals from the epidermal growth factor receptor to downstream effectors. It is found in a range of human malignancies, such as colorectal cancer, lung adenocarcinoma and thyroid cancer. Our warfarin sensitivity detection assay for gel electrophoresis is a polymerase chain reaction PCR-based assay, that amplifies regions of the CYP2C9 and VKORC1 genes using allele-specific oligonucleotide primers. The genomic DNA can be extracted from whole blood using DNA isolation kits. Our irinotecan toxicity test is a predictive test applied for assessing the risk of toxicity due to irinotecan-based chemotherapy. It detects polymorphic variants of UGT1A1 that cause the increase in toxicity associated with irinotecan. Our 5-FU toxicity test is used for assessing the risk of toxicity due to 5-FU based chemotherapy. We supply 5-FU based drugs such as Xeloda®, Adrucil®, Efudix®, Carac®, and Fluoroblastin®. Our Xeloda® is used for the treatment of metastatic breast and colorectal cancer.