Profile: ISTO Technologies is an orthobiologic company focused on developing differentiated products for spinal therapy, sports medicine, and trauma. Our product list comprises of bone graft extender & substitute, injectable cell-based therapy, and cartilage implants. Our product names are InQu™, NuQu™ and DeNovo® ET. The InQu bone graft extender & substitute combines the structural & biological attributes of polylactide-co-glycolide (PLGA) and hyaluronic acid (HyA). It supports the normal process of endochondral bone formation. The combination of PLGA and HyA provides the surgeon with superior cohesiveness, molding properties and handling characteristics to yield consistent, predictable results. NuQu is an early-stage development cell-based therapy aimed at resolving the cause of back pain associated with degenerative disc disease. It is composed of culture-expanded juvenile cartilage cells in a protein-based carrier.