Pre-processing sink is designed to accommodate the requirements of pre-processing the endoscope prior to automated washing and disinfecting. It provides adequate size and adaptation to the endoscope to remove gross contaminants. The sink chamber is of a size to provide sufficient space to accommodate all flexible and most rigid endoscopes and accessories, to manually wipe down the insertion tube of the endoscope, to brush the channels, and to soak the entire endoscope or accessory to loosen dried or stubborn debris.